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2013 22nd International Conference on Noise and Fluctuations (ICNF)
Brownian dynamics simulations provide evidence for a remote knock-on mechanism facilitating the permeation of a biological ion channel by an ion that is initially trapped at the selectivity filter (SF). Unlike the case of conventional direct knockon, the second ion that instigates permeation does not need to enter the channel. Nor does it necessarily take the place of the permeating ion at the SF, and it can even be of a different ionic species. The study is based on the simultaneous,doi:10.1109/icnf.2013.6578893 fatcat:crv56b4235fx3czixo5tznwsbu