Mediastinal tumors develop in specific locations. Neurogenic tumors appear most frequently in cases of posterior mediastinal tumors, followed by teratomas or benign tumors. Here, we have described two surgically treated cases of juvenile posterior malignant tumors with similar clinical courses of tumor growing and difficulty in preoperative diagnosis. Case Series: Case 1: A 32-year-old woman presented to our hospital with a right posterior mediastinal tumor detected during a medical checkup on

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... omputed tomography. Positron emission tomography-computed tomography and magnetic resonance imaging showed a neurogenic tumor. Tumor resection was performed via video-assisted thoracic surgery for the retrospectively evident growth. Pathological examination revealed a solitary fibrous tumor with immunohistochemical findings (vimentin/B-cell lymphoma 2 protein/STAT6 positivity).