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Sixteen metal ions viz; Li (I), Mg (II), Sr (II), Ca (II), Mn (II), Co (II), Ni (II), Cu (II), Zn (II), Cd (II), Ba (II), Pb (II), Al (III), Cr (III), Fe (III) and Th (IV) were selected to elucidate their interaction with folic acid using potentiometric method. The protonation and stability constants of formed complexes have been calculated using ionic strength, I = 0.2 M NaNO 3 in aqueous solutions at 25±0.1 ºC. Complexes of 1:1, 1:2 and/or 1:3 metal to ligand ratios were formed depending ondoi:10.20964/2017.02.06 fatcat:r3fdnniz25ghxkozsezwpdzi64