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Zingiberaceae COX-1 and -2 NF-κB Labdane diterpenes A B S T R A C T Hedychium coronarium J. Koenig, Zingiberaceae, is a medicinal plant popularly used to treat inflammatory conditions in different countries. Three labdane diterpenes [isocoronarin D (1), methoxycoronarin D (2), ethoxycoronarin D (3)] and benzoyl eugenol (4) were isolated from rhizomes and their chemopreventive potential was evaluated using in vitro assays, namely the inhibition of NF-κB, COX-1 and -2, the induction ofdoi:10.1016/j.bjp.2014.08.002 fatcat:yf44qgmrvzccvaj2ggvsgi6cmu