Assessment Of Biological Activity On Cirsium Arvense L

Md. Lokman Hossain, A.S.M. Monjur-Al-Hossain, Subarna Saha, Samir Kumar Sadhu
2017 Zenodo  
This study was aimed at evaluating antibacterial, cytotoxic, anthelmintic and anti-hyperglycemic activity of aerial part of Cirsium arvense. Antibacterial activity was determined by disc diffusion method at the concentration of 200, 250 and 500 µg/disc. Cytotoxic and anthelmintic activity was carried out according to Meyer and Gade method with slight modification respectively. The anti-hyperglycemic activity was determined by the method followed by Djilani. The extract showed dose dependent
more » ... dose dependent antibacterial activity against the experimental bacterial strains except Staphylococcus epidermidi, Streptococcus agalactiae and Enterococcus faecalis. In brine shrimp lethality bioassay, it showed LC50 at 51 µg/ml that is comparable to that of standard drug, vincristine sulphate (LC50 0.44 µg/ml). Also it showed dose dependent anthelmintic activity. It did not show anti-hyperglycemic activity. Our findings provide evidence that potential bioactive compounds are responsible for biological activities and further studies are required to isolate these compounds.
doi:10.5281/zenodo.824566 fatcat:3vfkz6vx3bcb3j7yremexqjmku