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Conformational Transition in SPR Experiments: Impact of spacer length, immobilization mode and aptamer density on signal sign and amplitude

Marina Pons, Marine Perenon, Hugues Bonnet, Emilie Gillon, Coelio Vallée, Liliane Guerente, Eric Defrancq, Nicolas Spinelli, Angéline Van der Heyden, Jérôme Dejeu
2022 The Analyst  

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Surface plasmon resonance (SPR) is an optical, real-time and label-free technique which represents a standard to study biomolecular interactions. While SPR signals are usually positive upon recognition, few cases of...
doi:10.1039/d2an00824f pmid:35983869 fatcat:q4ttlcv5lve5bnfqwtu3pizz54
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Marina Pons, Marine Perenon, Hugues Bonnet, Emilie Gillon, Coelio Vallée, Liliane Guerente, Eric Defrancq, Nicolas Spinelli, Angéline Van der Heyden, Jérôme Dejeu. "Conformational Transition in SPR Experiments: Impact of spacer length, immobilization mode and aptamer density on signal sign and amplitude." The Analyst (2022)