Sensitivity of Herd Strains of Klebsiella pneumoniae to Antibiotics and its Trend
Acta Veterinaria Brno
Mdz 0., F. Vymola, E. Vrbova: Sensitivity of Herd Strains of Klebsiella pneumoniae to Antibiotics and its Trend. Acta vet. Bmo, 50, 1981: 201-205. Sixty nine strains of KI. pneumoniae of almost exclusively bov~e origin (milk, nostrils, rectum and skin at the base of the udder) were examined and compared with 72 serotype strains of Danish origin isolated in 1955. Our main interest was focused at the contemporary sensitivity to the antibiotics and evaluation of its trend during the past 25 years.
... the past 25 years. In all experiments the disc method was employed, accomplished by the dilution micromethod for determination of the minimum inhibitory concentration of antibiotics in selected experiments. The following results were obtained: 1) From the total number of 30 preparations examined in both groups of KI. pneumoniae strains 14 antibiotics showed no effect (bacitracin, cephaloridine, erythromycin, fucidine, lincomycin, methicillin, novobiocin, nystatin, oleandomycin, oxacillin, penicillin, pristinamycin, spiramycin, vancomycin). 2) Therapeutically prospective results were obtained with cephalothin, gentamicin, kanamycin, colistin, neomycin, oxytetracycline, paromomycin, polymyxin B, streptomycin and tetracycline. Seventy five to 97.2 % of strains were resistant to ampi-