Identification of a single nucleotide polymorphism of the pituitary-specific transcriptional factor 1 (Pit 1) gene and its association with body composition trait in Iranian commercial broiler line
English

Rodbari Zahra, Alipanah Masoud, Reza Seyedabadi Hamid, Amirinia Cyrus
2011 African Journal of Biotechnology  
Pit-1 is a pituitary-specific transcriptional factor that has been shown to play a critical role both in cell differentiation during organogenesis of the anterior pituitary and as a transcriptional activator for pituitary gene transcription. This study was designed to investigate the associations of Pit-1 gene polymorphism on chicken body growth and body composition traits. Genomic DNA was extracted from 120 chickens from Iranian commercial broiler line. Two polymorphisms of the Pit-1 gene were
more » ... the Pit-1 gene were found with restriction fragment length polymorphisms. The association between these polymorphisms with chicken growth and body composition traits were analyzed using single marker analysis. Polymorphisms in Pit-1 gene were significantly (P<0.1) associated with body growth and body composition traits. This study suggests that Pit-1 gene could be a candidate locus or linked to major gene(s) that affects growth and body composition traits in the chicken.
doi:10.5897/ajb11.1149 fatcat:ntww3anbjfgajiepm2dkcdhxqe