Synthesis of N-arylsulfonylimidazolidine-4-ones from N-(2,2,2-trichloroethylidene)arenesulfonamides and monochloroacetamide

2003 ARKIVOC  
Dedicated to Academician Boris A. Trofimov on his 65 th birthday with heartiest wishes (Abstract The reaction of N-(2,2,2-trichloroethylidene)arenesulfonamides with monochloroacetamide involves nucleophilic addition to the C=N bond of the imine function, to give N-(arenesulfonamido-2,2,2-trichloroethyl)chloroacetamides. The latter, in the presence of bases, undergo intramolecular cyclization to give imidazole derivatives.
doi:10.3998/ark.5550190.0004.d06 fatcat:snsd6legnvfofl43mpzdoc346a