Effectiveness of iron supplementation for children with iron deficiency anemia: Study in Purbalingga, Central Java

Tien Budi Febriani, Emy Azmi Choironi, Latifah Hanum
2020 Jurnal kedokteran dan kesehatan Indonesia  
Iron Deficiency Anaemia (IDA) is one of major factors for human health, especially young children. Iron supplementation can indicate a good response in haemoglobin concentration. Objective: This study is to observe prevalence of anaemia and effectiveness of iron supplementation for children in Purbalingga district, Central Java. Methods: This study was a quasi-experimental study by measuring haemoglobin concentration before (pre) and after (post) treatment. Its participants were determined by a
more » ... ere determined by a purposive sampling method. 64 children (less than 5 years old) were included in criteria of anaemia. Their blood samples were collected before the treatment to measure SI (Serum Iron) and TIBC (Total Iron Binding Capacity). Administering 4 mg of iron per kg of body weight per day was conducted for a month. Data of participants such as age, nutritional status, socio-demographic, and medical history were also collected. A paired t-test was used to analyse mean differences of haemoglobin levels before and after treatment. Results: Among the 64 children with anaemia, 98.4% indicated Iron Deficiency (ID) with 59.4% of them indicating IDA based on level of SI and TIBC. Anaemia has more prevalence in group of 6 -<12 months of age. There was a statistically significant increase of haemoglobin level with a mean difference of 1.52 g/dL between the pre and post treatment (p=0.000). Conclusion: The prevalence of IDA in children (less than 5 years old) in Purbalingga District Hospital was 59.4%. Adequately oral iron supplementation for a month indicated a statistically significant increase of haemoglobin levels. Latar Belakang: Anemia Defisiensi Besi (ADB) adalah salah satu faktor utama dalam kesehatan manusia, terutama anak-anak. Suplementasi zat besi dapat menunjukkan respon yang baik terhadap konsentrasi hemoglobin. Tujuan: Penelitian ini bertujuan untuk mengobservasi prevalensi anemia dan efektivitas pemberian zat besi untuk anak-anak di kabupaten Purbalingga, Jawa Tengah. Metode: Penelitian ini adalah penelitian quasi-eksperimen yang mengukur jumlah konsentrasi hemoglobin sebelum (pra) dan setelah (pasca) perawatan. Para peserta yang menjadi subyek dalam penelitian ini ditentukan dengan metode purposive sampling. 64 anak-anak (di bawah 5 tahun) termasuk dalam kriteria anemia. Sampel darah mereka dikumpulkan sebelum perawatan dilaksanakan untuk mengukur Serum Iron (SI) dan Total Iron Binding Capacity (TIBC). Pemberian 4 mg zat besi per kg berat badan per hari dilakukan selama sebulan. Data peserta dalam penelitian ini seperti usia, status gizi, sosio-demografis, dan riwayat medis juga dikumpulkan. Uji t-berpasangan digunakan untuk menganalisisa perbedaan rata-rata kadar
doi:10.20885/jkki.vol11.iss1.art11 fatcat:nwkyffoaj5ezdpn5oe6ffzj53u