Figure S1: Supplemental images of TGFβ2 KO coloboma phenotypes from TGFβ-facilitated optic fissure fusion and the role of bone morphogenetic protein antagonism

Max D. Knickmeyer, Juan L. Mateo, Priska Eckert, Eleni Roussa, Belal Rahhal, Aimee Zuniga, Kerstin Krieglstein, Joachim Wittbrodt, Stephan Heermann
2018 Figshare  
(A) Serial frontal sections (E18.5, H&E) of a TGFβ2 KO embryo from mixed genetic background. The optic fissure margins did not fuse but grew inwards. Scale bars represent 200µm. (B) Serial frontal sections (E18.5, H&E) of a TGFβ2 KO embryo from mixed genetic background. In addition to the usual coloboma phenotype, there is a dorsal coloboma. Scale bars represent 200µm. (C) Serial frontal sections (E18.5, H&E) of a TGFβ2/GDNF double KO embryo. In addition to the usual coloboma phenotype, there
more » ... phenotype, there is a dorsal coloboma. Scale bars represent 200µm.ted fish as control.
doi:10.6084/m9.figshare.5999822 fatcat:kxmfd37bgjfwbeyzsdzvipud2u