An image analysis method for quantification of hepatic perfusion based on contrast-enhanced ultrasound imaging

Yi-xin Li, Fang Yang, Ning Gu
2008 Journal of Biomedical Science and Engineering  
Information about hepatic perfusion is used in clinical liver disease diagnosis. An image analysis system can help physicians make efficient and accurate diagnosis. The objective of this study is to propose an image analysis method for the quantification of the hepatic perfusion based on contrast-enhanced ultrasound imaging (CEUI). The proposed method contains frame selection, image registration, digital subtraction and grey-scale calculation. Then, by processing an image sequence, a
more » ... uence, a time-intensity curve (TIC) for hepatic perfusion is derived. The kernel of this image analysis technology is digital subtraction and its accuracy is improved by frame selection and image registration. The advantage of this method is that it can obtain the perfusion information of the whole liver which is rarely obtained by traditional image analysis technology; therefore, it is a supplement of the traditional image analysis method. This method is applied on the quantification of a rabbit's hepatic perfusion and the result shows the efficiency of it.
doi:10.4236/jbise.2008.12019 fatcat:npbfgoygozfavp7stnuoqhwpna