Purpose: Our aim was to compare the accuracy of intraocular lens (IOL) power calculation with two techniques namely optical biometry based on partial coherence laser interferometry (PCLI) principle and conventional ultrasound biometry. Materials and Methods: A comparative study was done in our hospital wherein 100 eyes of 100 patients undergoing phacoemulsification cataract surgery were recruited into it. Out of them, 50 eyes underwent optical biometry and 50 eyes underwent conventional

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... ion ultrasound biometry. Eyes were grouped according to axial length into long (>24.50), normal (22 to <24.50) and short (<22mm). Paired t-tests were applied and the mean error and mean absolute error (MAE) were calculated. Results: The MAE calculated was 0.60 +/-0.40D and 0.20+/-0.30D with the conventional applanation ultrasound and optical biometry respectively. It was found that the optical biometry gives more accurate values for eyeball with small and large axial length. Conclusion: The optical biometry parameters which uses the partial coherence laser interferometry (PCLI) principle happens to be the more precise method in IOL power calculation.