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Human brucellosis is a public health problem worldwide. Neurobrucellosis is a rare and severe form of systemic infection and has a broad range of clinical syndromes. Case Presentation: We reported a 21-year-old woman who was referred to our clinic with a subacute onset of fever, myalgia, and weakness of right foot, which gradually progressed and involved lower limbs and culminated in total paralysis. Conclusions: Although neurobrucellosis is a rare presentation of disease, meningitis ordoi:10.17795/iji-21561 fatcat:qkmmeraalvh4vfpn5ozuxtwmr4