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Reusability of sensors is relevant when aiming to decrease variation between measurements, cost and time of analysis. We present an electrochemically assisted surface-enhanced Raman spectroscopy (SERS) platform with the capability to reverse the analyte-surface interaction, without damaging the SERS substrate, allowing for efficient sensor reuse. The platform was used in combination with a sample pre-treatment step, when detecting melamine from milk. We found that the electrochemically enhanceddoi:10.1021/acs.analchem.9b05060.s001 fatcat:33srqte7tfcqrojz7ykz3taseq