This paper present area efficient layout designs for 3.3GigaHertz (GHz) Phase Locked loop (PLL) with four multiple output. Effort has been taken to design Low Power Phase locked loop with multiple output, using VLSI technology. VLSI Technology includes process design, trends, chip fabrication, real circuit parameters, circuit design, electrical characteristics, configuration building blocks, switching circuitry, translation onto silicon, CAD and practical experience in layout design. The

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... d PLL is designed using 45 nm CMOS/VLSI technology with microwind 3.1. This software allows designing and simulating an integrated circuit at physical description level. The main novelties related to the 45 nm technology are the high-k gate oxide, metal gate and very low-k interconnect dielectric. The effective gate length required for 45 nm technology is 25nm. Low Power (0.211miliwatt) phase locked loop with four multiple outputs as PLL8x, PLL4x, PLL2x, & PLL1x of 3.3 GHz, 1.65 GHz, 0.825 GHz, and 0.412 GHz respectively is obtained using 45 nm VLSI technology. Index Terms : phase-locked loop (PLL), high performance voltage-controlled oscillator (VCO), 45nm technology, multiple outputs, low power.