Desreplicação de alcaloides aporfínicos e oxoaporfínicos de Unonopsis guatterioides por ESI-IT-MS

Felipe Moura Araújo da Silva, Hector Henrique Ferreira Koolen, Richardson Alves de Almeida, Afonso Duarte Leão de Souza, Maria Lúcia Belém Pinheiro, Emmanoel Vilaça Costa
2012 Química Nova  
Recebido em 14/7/11; aceito em 25/11/11; publicado na web em 20/1/12 DEREPLICATION OF APORPHINE AND OXOAPORPHINE ALKALOIDS FROM Unonopsis guatterioides BY ESI-IT-MS. The dereplication of aporphine and oxoaporphine alkaloids by direct infusion in ESI-IT-MS n system was applied for alkaloidal fractions of the Unonopsis guatterioides (Annonaceae). Its main advantage over other dereplication methods is the ability to quickly identify substances in complex mixtures without the use of coupled
more » ... of coupled techniques and expensive databases. By only the fragmentation keys and comparison with literature data the aporphine alkaloids anonaine, asimilobine and nornuciferine were identified. The nornuciferine is being reported for the first time in Unonopsis. The oxoaporphine alkaloids liriodenine and lisycamine were identified in the alkaloidal fractions by comparison with the fragmentations of authentic samples.
doi:10.1590/s0100-40422012000500015 fatcat:z5bs55d4wjdvljd7uyjg7leyhu