Synthesis of a new class of naphthoquinone glycoconjugates and evaluation of their potential as antitumoral agents

Vinicius R. Campos, Anna C. Cunha, Wanderson A. Silva, Vitor F. Ferreira, Carla Santos de Sousa, Patrícia D. Fernandes, Vinícius N. Moreira, David R. da Rocha, Flaviana R. F. Dias, Raquel C. Montenegro, Maria C. B. V. de Souza, Fernanda da C. S. Boechat (+2 others)
2015 RSC Advances  
A novel series of carbohydrate-based naphthoquinones was synthesized and evaluated for cytotoxicity against different human cancer cell lines (HCT-116, A-549 and MDA-MB 435). The compounds derived from juglone showed better cytotoxicity profiles.
doi:10.1039/c5ra19192k fatcat:hkmzbz4ncjgtbfbqgduhe233lq