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ings from those of five years previous. Vaccine therapy is advocated in the treatment of all of these affections and Allen reports good results in their cure and in the matter of immunization, but the fact is emphasized that all work must be controlled by the most careful bactériologie determinations. Immunity, he says, probably depends more on the chemical composition of the tissues, as determined by metabolic processes, than is at present realized. In the discussion of vaccine, and tuberculindoi:10.1001/jama.1913.04350150074033 fatcat:7us233hsuvej7hj27parwidxfe