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We recently implicated a cluster of nine single nucleotide polymorphisms from seven cholesterolrelated genes in the risk of Alzheimer's disease (AD) in a European cohort, and we proposed calculating an aggregate cholesterol-related genetic score (CREGS) to characterize a person's risk. In a separate study, we found that apolipoprotein E (APOE) ε4 gene dose, an established AD risk factor, was correlated with fluorodeoxyglucose (FDG) positron emission tomography (PET) measurements ofdoi:10.1016/j.neuroimage.2007.12.066 pmid:18280754 pmcid:PMC2441925 fatcat:odwj5jtkxvhhffjv3wtzemkala