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The effect of aminoglycosides on horizontal gene transfer in Klebsiella pneumoniae
2020
Revista de la Academia Colombiana de Ciencias Exactas Físicas y Naturales
Antibiotic-resistant bacteria represent a global risk to public health. Horizontal gene transfer, a common mechanism for genetic exchange in bacteria, plays an essential role in the acquisition of resistance genes. In this work, we evaluated the effect of sub-lethal concentrations of antibiotics on plasmid transfer by conjugation and transformation in the opportunistic pathogen Klebsiella pneumoniae. Despite not being naturally competent, this bacterium could acquire extracellular DNA from
doi:10.18257/raccefyn.985
fatcat:dbwpisd3wfgrzp75pvctevcmdy