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Effect of kanglaite on rat cytochrome P450
2014
Pharmaceutical Biology
Context: Kanglaite (KLT) is an oily substance extracted from Coix lacryma-jobi Linn. (Cramineae) and has been proved to significantly improve the life span and quality of life of patients, when combined with chemotherapy, radiotherapy, or surgery. Objective: The purpose of this study was to find out whether KLT influences the effect on rat cytochrome P450 (CYP) enzymes (CYP1A2, CYP2B6, CYP2C9, CYP2C19, and CYP3A4) by using cocktail probe drugs in vivo. Materials and methods: A cocktail solution
doi:10.3109/13880209.2014.952833
pmid:25472767
fatcat:k6we7lw7kfh23hy3dgvdoxmlla