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High throughput screening (HTS) enables systematic testing of thousands of chemical compounds for potential use as investigational and therapeutic agents. HTS experiments are often conducted in multi-well plates that inherently bear technical and experimental sources of error. Thus, HTS data processing requires the use of robust quality control procedures before analysis and interpretation. Here, we have implemented an open-source analysis application, Breeze, an integrated quality control anddoi:10.1093/bioinformatics/btaa138 pmid:32119072 pmcid:PMC7267830 fatcat:kqstvjud3jcafgfafs33vnntly