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Minerva: An Alignment and Reference Free Approach to Deconvolve Linked-Reads for Metagenomics
Emerging linked-read technologies (aka read-cloud or barcoded short-reads) have revived interest in standard short-read technology as a viable way to understand large scale structure in genomes and metagenomes. Linked-read technologies, such as the 10X Chromium system, use a microfluidic system and a set of specially designed 3 prime barcodes (aka UIDs) to tag short DNA reads which were originally sourced from the same long fragment of DNA; subsequently these specially barcoded reads aredoi:10.1101/217869 fatcat:ubg27u5d3fan3ohcyajytu3szu