Acquisition and processing of a conditional dicentric chromosome in Saccharomyces cerevisiae

K Bloom, A Hill
1989
The introduction of a conditional centromere into chromosome III of Saccharomyces cerevisiae provided an opportunity to evaluate phenotypic and karyotypic consequences in cells harboring dicentric chromosomes upon entry into mitosis. A mitotic pause ensued, and monocentric derivatives of chromosome III were generated at a high frequency.
doi:10.17615/zvxb-ee39 fatcat:ere2wir735akpptucuwsinpghq