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Evolutionary variation of papillomavirus E2 protein and E2 binding sites
2011
Virology Journal
In an effort to identify the evolutionary changes relevant to E2 function, within and between papillomavirus genera, we evaluated the E2 binding sites (E2BS)s inside the long-control-region (LCR), and throughout the genomes. We identified E2BSs in the six largest genera of papillomaviruses: Alpha, Beta, Gamma, Delta, Lambda, and Xi-papillomaviruses (128 genomes), by comparing the sequences with a model consensus we created from known functional E2BSs (HPV16, HPV18, BPV1). We analyzed the
doi:10.1186/1743-422x-8-379
pmid:21806797
pmcid:PMC3161962
fatcat:hsi5gqhitrerxecybe4ibqeo2u