p<0.05), P5-LSR was higher than P1-LSR (p<0.05). The area under the ROC curve was 0.812 in model that associate mechanical and morphological parameters. Sensitivity and specificity was 78% and 84% separately at the cut-off point. Conclusion Measurement of mechanical parameters provides a noninvasive approach to the evaluation of plaque mechanical conditions, which is associated with ischaemic cerebralvascular disease. A characteristic of asymmetry was detected among different locations on carotid plaques especially in symptomatic subjects.