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Validation of multiplex steroid hormone measurements in prostate cancer using plasma for multimodality biomarker studies
[article]
2020
medRxiv
pre-print
Steroid hormones are essential signaling molecules in prostate cancer (PC). However, many studies focusing on liquid biomarkers fail to take hormonal status of these patients into account. Because steroid measurements are sensitive to bias caused by matrix effects, thus assessing potential matrix effects is an important step in combining ctDNA analysis with hormone status. Methods We investigated the accuracy of multi-steroid hormone profiling in mechanically-separated plasma tubes (MSP) and in
doi:10.1101/2020.08.05.20164202
fatcat:oo4csefv4jgmvh3hjjl3piwql4