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Effect of an anorexiant on levels of 5-HIAA and GSH in brain of well-nourished and malnourished rats
African Journal of Pharmacy and Pharmacology
In this study, the effect of sibutramine and carnitine on 5-HIAA and GSH levels in brain regions of malnourished rats was analyzed. Twenty-four rats were fed with a normal protein diet (23%) and another similar group with protein starvation diet (7%). The animals of both groups were re-assigned into four groups of 6 animals per group and treated for 10 days as follows: group 1, saline solution; group 2, sibutramine (10 mg/kg); group 3, carnitine (500 mg/kg); and group 4, sibutramine (10 mg/kg)doi:10.5897/ajpp2013.3876 fatcat:feadxi5vxjfvrievqheohz7moi