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Reactive oxygen and nitrogen species in the course of B-CLL
2007
Advances in Medical Sciences
The study objective was to investigate the production of NO, cGMP and superoxide anion radical by neutrophils, and to examine alterations in serum or plasma total nitric oxide, MDA and cGMP levels in B-CLL patients. PMNs were isolated from 20 patients with B-CLL. Total nitrite was measured in cell supernatants and serum by Griess method. The generation of superoxide anion radical by cells was estimated using cytochrom-c reduction test. The cGMP level in cell supernatants and plasma was assessed
pmid:18217409
fatcat:nddyoem77zga5jveg5bgbdawku