Ecological interventions to prevent and manage zoonotic pathogen spillover

Susanne H. Sokolow, Nicole Nova, Kim M. Pepin, Alison J. Peel, Juliet R. C. Pulliam, Kezia Manlove, Paul C. Cross, Daniel J. Becker, Raina K. Plowright, Hamish McCallum, Giulio A. De Leo
2019 Philosophical Transactions of the Royal Society of London. Biological Sciences  
Spillover of a pathogen from a wildlife reservoir into a human or livestock host requires the pathogen to overcome a hierarchical series of barriers. Interventions aimed at one or more of these barriers may be able to prevent the occurrence of spillover. Here, we demonstrate how interventions that target the ecological context in which spillover occurs (i.e. ecological interventions) can complement conventional approaches like vaccination, treatment, disinfection and chemical control.
more » ... ng spillover owing to environmental change requires effective, affordable, durable and scalable solutions that fully harness the complex processes involved in cross-species pathogen spillover. This article is part of the theme issue 'Dynamic and integrative approaches to understanding pathogen spillover'.
doi:10.1098/rstb.2018.0342 pmid:31401951 pmcid:PMC6711299 fatcat:gzwrqsmcbfhlja65on7gpf5f5e