The Function of the Social Service of the Psychopathic Hospital, Boston
Boston Medical and Surgical Journal
Analyzing the causes of the four deaths occurring among cases treated with vaccines, we find the first death due to an intestinal perforation, after the fifth inoculation of vaccine and after patient had received a total of 150 million dead bacilli ; the second death was due to septic parotitis developing during a relapse which began after three weeks without fever and after patient had received 880 million killed bacteria ; the third death was due to an intestinal hemorrhage occurring on
... occurring on eighteenth day after patient's admission to the hospital and after he had received 530 million dead organisms; the fourth death was due to bronchopneumonia on patient's twenty-first day in hospital and after he had received 580 million killed typhoid bacilli. These deaths were obviously not due to complications extraneous to typhoid fever. The deaths occurring among the 95 cases not "inoculated with dead typhoid bacilli were as follows : 4 pneumonia, 2 hemorrhage, 3 severity of the disease, 1 perforation, 1 alcoholism. The more important articles which suggested this work were as follows : First that by Callison, pathologist to the Manhattan Eye, Ear and Throat Hospital in American Journal Medical Sciences for September, 1913, wherein he reports 475 cases of typhoid fever treated with vaccines by various men and showing a mortality of 6.5% and a 6.5% incidence of relapse. Second, the work of Captain Smallman of the English Army Medical Corps, who reports 36 cases of typhoid fever treated with vaccines, having a mortality of 8.3%. Third, the report of 41 cases by Meakins of the Royal Victoria Hospital, Montreal, where he used from 1000 tc 4500 million killed bacteria-polyvalent nonautogenous vaccine,-with the death-rate oi 4.6% and incidence of relapse of 2.3% amoiif: cases so treated, contrasted with a death-rate o: 12.2% and an incidence of relapse of 13â mong eases not vaccinated. In the endeavor to be conservative and mind ful of the absence of any good theoretical basi; for the use of vaccines in cases of septicemia, th dosage used in this series was small, but fre quently repeated. The value of this work is entirely negative Using the kind of vaccine and the doses airead; outlined, we find, first, no obvious systemic re action to the vaccines; second, a local reactio: to every inoculation with dead organisms, an third, no diminution of the duration of fever i: uncomplicated cases nor of the incidence o complications, nor of mortality. RlNDElU'EST IN THE PHILIPPINES.-Report from Manila, P. I., on June 15 states that the rinderpest or cattle-plague is rapidly spreading in the islands. Means are being taken to prevent its further extension.