Two new flavanes, (2S)-4′ ,7-dihydroxy-6,8-dimethylflavane (1), and (2S)-5,7-dihydroxy-4′-methoxy- 8-methylflavane (2), together with five known flavanes, (2S)-3′ ,7-dihydroxy-4′-methoxy-8- methylflavane (3), (2R)-4′,7-dihydroxy-8-methylflavane (4), (±)-3′,7-dihydroxy-4′-methoxyflavane (5), (±)-4′,7-dihydroxy-3′-methoxyflavane (6), and (2S)-4′,7-dihydroxyflavane (7), were isolated from the stem of Dracaena cambodiana. Their structures were determined by spectroscopic techniques (UV, IR, 1D and

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... D NMR). Their antimicrobial activities were preliminarily examined by the filter paper disc agar diffusion method.