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Frequency of hepatitis B surface antigen variants (HBsAg) in hepatitis B virus genotype B and C infected East- and Southeast Asian patients: Detection by the Elecsys ® HBsAg II assay
Journal of Clinical Virology
To avoid false negative results, hepatitis B surface antigen (HBsAg) assays need to detect samples with mutations in the immunodominant 'a' determinant region, which vary by ethnographic region. Objective: We evaluated the prevalence and type of HBsAg mutations in a hepatitis B virus (HBV)-infected Eastand Southeast Asian population, and the diagnostic performance of the Elecsys ® HBsAg II Qualitative assay. Study design: We analyzed 898 samples from patients with HBV infection from four sitesdoi:10.1016/j.jcv.2018.04.005 pmid:29655170 fatcat:w6scetd6jzhnnk35clr5yo3hdu