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Rab18 is not necessary for lipid droplet biogenesis or turnover in human mammary carcinoma cells
Molecular Biology of the Cell
Rab18 is not necessary for lipid droplet biogenesis or turnover in human mammary carcinoma cells ABSTRACT Rab GTPases recruit peripheral membrane proteins and can define organelle identity. Rab18 localizes to the endoplasmic reticulum (ER) but also to lipid droplets (LDs), where it has been implicated in effector protein recruitment and in defining LD identity. Here, we studied Rab18 localization and function in a human mammary carcinoma cell line. Rab18 localized to the ER and to LD membranesdoi:10.1091/mbc.e18-05-0282 pmid:29949452 fatcat:zyhxx6utdfenhagsvp6tbthcya