The versatile functions of OsALDH2B1 provide a genic basis for growth–defense trade-offs in rice

Yinggen Ke, Meng Yuan, Hongbo Liu, Shugang Hui, Xiaofeng Qin, Jie Chen, Qinglu Zhang, Xianghua Li, Jinghua Xiao, Qifa Zhang, Shiping Wang
2020 Proceedings of the National Academy of Sciences of the United States of America  
In plants, enhanced defense often compromises growth and development, which is regarded as trade-offs between growth and defense. Here we identified a gene, OsALDH2B1, that functions as a master regulator of the growth–defense trade-off in rice. OsALDH2B1 has its primary function as an aldehyde dehydrogenase and a moonlight function as a transcriptional regulator. Loss of function of OsALDH2B1 greatly enhanced resistance to broad-spectrum pathogens, including fungal blast, bacterial leaf
more » ... cterial leaf blight, and leaf streak, but caused severe phenotypic changes such as male sterility and reduced plant size, grain size, and number. We showed that its primary function as a mitochondrial aldehyde dehydrogenase conditions male fertility. Its moonlight function of transcriptional regulation, featuring both repressing and activating activities, regulates a diverse range of biological processes involving brassinolide, G protein, jasmonic acid, and salicylic acid signaling pathways. Such regulations cause large impacts on the morphology and immunity of rice plants. The versatile functions of OsALDH2B1 provide an example of the genic basis of growth–defense trade-offs in plants.
doi:10.1073/pnas.1918994117 pmid:32024752 fatcat:5ltilivkifb63hczbdjjll23iy