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Antituberculosis activities of clofazimine and its new analogs B4154 and B4157
Antimicrobial Agents and Chemotherapy
In our efforts to develop new drugs for the treatment of tuberculosis, especially that caused by multidrug-resistant strains, we investigated clofazimine (CFM) and two of its analogs, B4154 and B4157, for their antituberculosis activities. Twenty M. tuberculosis strains were tested, including 16 drug-resistant strains (strains resistant to one or more antituberculosis drugs), for their susceptibilities to these three agents. All of the strains were found to be susceptible to B4154 and B4157,doi:10.1128/aac.40.3.633 fatcat:z353ygssnfhhlalvkxilecnrjm