Organocatalysis and Beyond: Activating Reactions with Two Catalytic Species

Arianna Sinibaldi, Valeria Nori, Andrea Baschieri, Francesco Fini, Antonio Arcadi, Armando Carlone
2019 Catalysts  
Since the beginning of the millennium, organocatalysis has been gaining a predominant role in asymmetric synthesis and it is, nowadays, a foundation of catalysis. Synergistic catalysis, combining two or more different catalytic cycles acting in concert, exploits the vast knowledge acquired in organocatalysis and other fields to perform reactions that would be otherwise impossible. Merging organocatalysis with photo-, metallo- and organocatalysis itself, researchers have ingeniously devised a
more » ... iously devised a range of activations. This feature review, focusing on selected synergistic catalytic approaches, aims to provide a flavor of the creativity and innovation in the area, showing ground-breaking examples of organocatalysts, such as proline derivatives, hydrogen bond-mediated, Cinchona alkaloids or phosphoric acids catalysts, which work cooperatively with different catalytic partners.
doi:10.3390/catal9110928 fatcat:lywndzlt3jdxflrk7zvgvoquq4