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Effects related to the neutron to proton ratio (N/Z) degree of freedom in 40,48 Ca+ 40,48 Ca reactions at 25 MeV/nucleon have been investigated. Isotopic effect and even-odd staggering characterize the emission of light fragments at forward angles. The study of isobaric ratio 7 Li/ 7 Be for quasi-projectile source in semi-peripheral event of reactions allows moreover to investigate isospin diffusion effects in heavy ion collisions. This is an Open Access article distributed under the terms ofdoi:10.1051/epjconf/20123100016 fatcat:5ttxvfavkbftzg6dxki6en2zwi