A Simultaneous X-Ray/MRI and Noncontact Mapping Study of the Acute Hemodynamic Effect of Left Ventricular Endocardial and Epicardial Cardiac Resynchronization Therapy in Humans

M. R. Ginks, P. D. Lambiase, S. G. Duckett, J. Bostock, P. Chinchapatnam, K. Rhode, M. J. W. McPhail, M. Simon, C. Bucknall, G. Carr-White, R. Razavi, C. A. Rinaldi
2011 Circulation: Heart Failure  
According to current guidelines, candidates for cardiac resynchronization therapy (CRT) are patients in New York Heart Association functional class III to IV heart failure with left ventricular (LV) ejection fraction Յ35% and QRS duration Ն120 ms. However, by applying these selection criteria, more than one third of the patients do not show clinical response or LV reverse remodeling. Among several factors that determine a favorable response to CRT, the amount of LV fibrosis as assessed, for
more » ... ple, with cardiovascular magnetic resonance has been shown to be an important issue. This study demonstrated that myocardial ultrasound reflectivity is an important determinant of CRT response in the overall heart failure Correspondence to The Editors, Circulation: Cardiovascular Imaging Editorial Office, Summary: Left ventricular hypertrophy (LVH), defined as increased indexed LV mass, is presently classified based on the ratio of the LV e16 Circ Cardiovasc Imaging
doi:10.1161/circheartfailure.110.958124 pmid:21216832 fatcat:j5zjfxpzk5hbncrxpfemszsj6m