Current available therapies and future directions in the treatment of malignant gliomas

James Vredenburgh
2008 Biologics : Targets & Therapy  
The prognosis of patients diagnosed with malignant glioma (MG) remains poor. However, recent advances in neuro-oncology allowing a better understanding of this particular disease have allowed the development of new therapeutics. Many molecular genetic and signal transduction pathway targets have been identifi ed that are now being investigated. Novel locoregional treatments, as well as strategies to improve regional delivery, are being evaluated. Studies of combinations of these approaches are
more » ... lso underway. In this review, we will discuss the current and future therapies under evaluation for the treatment of malignant gliomas.
doi:10.2147/btt.2009.2727 fatcat:s4gbngjhhfavhlvejapq3gjxky