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Stevens-Johnsons syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare cases of adverse cutaneous reactions that can be associated with the use of sulfasalazine. Clinicians, as well as patients, need to be aware of the signs and symptoms that often precede the appearance of the diffuse exfoliations lesions in an SJS or TEN. The associated symptoms should be marked, and immediate withdrawal of the offending medication should be done when blisters or erosions appear in the course of a drugdoi:10.21276/ijprhs.2019.03.01 fatcat:7mkq2boieva7lj3zotzsjw3csm