Polysaccharide derivatives as useful chiral stationary phases in high-performance liquid chromatography

Xiaoming Chen, Chiyo Yamamoto, Yoshio Okamoto
2007 Pure and Applied Chemistry  
The chromatographic separation of enantiomers using chiral stationary phases (CSPs) has significantly advanced. The esters and carbamates of polysaccharides coated on silica gel have been extensively studied and widely used as CSPs for high-performance liquid chromatography (HPLC). In order to overcome the strict solvent limitation on these coated CSPs, the preparation of a new generation of CSPs consisting of immobilized polysaccharide derivatives has become increasingly important. The
more » ... l solvent compatibility of the new CSPs provides flexibility in both analytical and preparative chromatographies.
doi:10.1351/pac200779091561 fatcat:oz5yw7jexncedlcheoc5vqack4