Unusual initial presentation of type 1 diabetes mellitus

Sundus Abbasi, Bradley Bradford
2014 International Journal of Contemporary Pediatrics  
A 21 year-old Caucasian girl presented to her pediatrician with a three day history of pre-tibial numbness extending from her knee to her ankle. She denied numbness in this area or elsewhere on her body before. She denied any traumatic event. She noted a 70-pound unintentional weight loss over the past 9 months. She described the numbness as "pins and needles". She denied pain, muscle weakness, difficulty walking, altered mental status, polydipsia, polyuria, and polyphagia. She denied tobacco,
more » ... he denied tobacco, alcohol, or drug use. Her past surgical history was unremarkable. Her family history was significant for sarcoidosis, thyroid cancer, and T1DM. ABSTRACT Type 1 Diabetes Mellitus (T1DM) is an autoimmune destruction of B-islet cells. T1DM usually presents in children less than 15 years old with polyuria, polydipsia, polyphagia, and weight loss. Complications include diabetic ketoacidosis, hypoglycemia, retinopathy, neuropathy, nephropathy, and atherosclerosis. We present an unusual initial presentation for T1DM in a 21-year old Caucasian girl with pretibial numbness for three days.
doi:10.5455/2349-3291.ijcp20140806 fatcat:sgqipxnnhzf25lue2azuafh3ju