A Novel Taxatetraene Framework Formed From a New Natural Taxane from Taxus cuspidata

Y. Li, Y.-L. Wang, Z.-Y. Ni, M. Dong, B. Cong, F. Sauriol, M.-L. Zhang, Y.-F. Wang, C.-H. Huo, Y.-C. Gu, Q.-W. Shi, H. Kiyota
2011 Zeitschrift für Naturforschung. B, A journal of chemical sciences  
Sinenxan H [2α,14β -diacetoxytaxa-4(20),11-diene-5α, 10β -diol, 1] was isolated from the heartwood of Taxus cuspidata, for the first time from natural sources. Compound 1 was found to be readily converted into 2α-acetoxytaxa-4(20),10,12(18),13-tetraen-5α-ol (2), the first example of a taxane with 10,11-and/or 13,14-double bond(s) and a conjugated triene system, in CDCl 3 .
doi:10.5560/znb.2011.66b0759 fatcat:e6ysaglcrrgjzockmd3egqgwlm