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A stability indicating RP-HPLC method was developed for the simultaneous estimation of the anti hypertensive drugs Hydrochlorothiazide, Amlodipine Besylate and Telemisartan. These drugs were subjected to stress studies under different conditions as per ICH guidelines. The separations were carried out using C 18 reverse phase column (Agilent ODS UG 5 column, 250mm x 4.5mm,5µm) employing Acetonitrile and Acetate buffer (60:40 v/v) as mobile phase and pH adjusted to 5 at flow rate of 1ml/min wasdoi:10.13005/ojc/320340 fatcat:2tinixqejfbv3j25e7s6acjufe