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Efficacious targeted drug delivery systems have been a dream for a long time but the chemistry hold complex form had made conditions complicated butthe expansion of new colloidal carrier called Nanosponges likely circumvent these problems. They consist of nanoporous particles that can suspend or entrap a wide variety of substances, and then be engulfed into a dosage form. They release their active components on a time mode and also in response to other stimuli (rubbing, temperature, pH etc.).doi:10.5281/zenodo.1443182 fatcat:hefgkwjucfclvjyun7hwdtwsve