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Swiss Medical Weekly
The earliest attempts at cell therapy can be attributed to Charles-Edward Brown-Séquard (1817–1894), who sought to treat senescence and aging by injecting animal gonad shreds into his contemporaries, a practice that was widespread in late 19th century. Since then, advances in science have enabled the development of biological substitutes to restore the function of various tissues. Skin was one of the first tissues to be regenerated. For severe burns, patient survival depends on the restorationdoi:10.4414/smw.2019.20079 pmid:31104308 fatcat:m4kz5k2n6jenlde4nqsc2kmlti