Mid-long-term surgical outcomes of posterior only instrumented spinal fusion procedure for early-onset scoliosis in type 1 neurofibromatosis [post]

2019 unpublished
The pediatric neurofibromatosis type 1 (NF-1) patients' mid-long-term surgical outcomes of posterior spinal fusion is rarely reported, and the orthopedic maintenance effect is not clear. This study aims to evaluate the mid-long-term surgical outcomes of posterior only instrumented spinal fusion for early-onset scoliosis (EOS) in NF-1 patients. Methods A retrospective review was performed on a cohort of 10 patients diagnosed as NF-1 with EOS from 2008 to 2014 in our hospital. This study included
more » ... This study included four male and six female NF-1 patients with a mean age of 7.8 years old when they underwent posterior only instrumented spinal fusion for their EOS. General clinical data, operation-related data were reviewed, and the dystrophic progression of EOS was evaluated during the follow-up. Results The mean follow-up duration was 54 months (24 to 88 months). All patients underwent posterior only instrumented spinal fusion at 1 stage. The primary curves of EOS were thoracic in 9 cases, and only one patient had lumbar scoliosis. Preoperative major curve was significantly corrected (from 66.1 to 31.1 degrees). However, the average major curve deteriorated significantly to 40.1 degrees on average at the end of follow-up. The T1-S1 distance increased 2.77cm on average and increasing at 0.6cm/year during the follow-up. Conclusions For the surgical treatment on EOS in NF-1 patients, although with relatively short segments involvements,posterior only fusion was not good way to treat such patients, especially the maintenance of orthopedic effect was not satisfactory.
doi:10.21203/rs.2.13661/v1 fatcat:j5bg7nqcqbgjfomtnndm2pcgue