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Immune Reconstitution Inflammatory Syndrome(IRIS) is defined as paradoxical deterioration in clinical status after Anti Retroviral Therapy(ART) initiation despite improved immune function due to inflammatory response against infectious agent, which may or may not be diagnosed at initiation of ART. Tuberculosis is most common opportunistic infection in HIV patients. Though it can present at any stage of HIV infection, it appears more commonly when CD4 count is around 350cells/microL. In advanceddoi:10.6084/m9.figshare.1355501.v1 fatcat:6xug7iif7jasfgtde2ae3z4lgi